- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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The N-terminal of ZO1 may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
Titration of the ZO1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This ZO1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1328-1362 amino acids from the C-terminal region of human TJP1/ZO1.
Aliquot the ZO1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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