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Home >> Antibodies >> ZNF238 Antibody

ZNF238 Antibody (F53853)

  Catalog No Formulation Size Price (USD)  
Image F53853-0.2ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.2 ml 399
Image
F53853-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 185
Bulk quote request
Western blot testing of mouse brain lysate with ZNF238 antibody at 1:2000. Predicted molecular weight: 58 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse
Predicted Reactivity Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q99592
Applications Western blot : 1:1000-2000
Limitations This ZNF238 antibody is available for research use only.
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Description

Zinc finger protein 238 is a transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'- [AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus.

Application Notes

Titration of the ZNF238 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 318-331 from the human protein was used as the immunogen for the ZNF238 antibody.

Storage

Aliquot the ZNF238 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Cross
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