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Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [UniProt]
Optimal dilution of the Yeast Histone H2B antibody should be determined by the researcher.
A synthetic peptide specific to yeast Histone H2B (Yeast) was used as the immunogen for the Yeast Histone H2B antibody.
Store the Yeast Histone H2B antibody at -20oC.
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