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- Email: info@nsjbio.com
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The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Titration of the XRCC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 228-254 from the human protein was used as the immunogen for this XRCC6 antibody.
Aliquot the XRCC6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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