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Home >> Antibodies >> XPB Antibody

XPB Antibody (RQ4567)

  Catalog No Formulation Size Price (USD)  
Image RQ4567 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) rat testis and 2) mouse testis lysate with XPB antibody at 0.5ug/ml. Predicted molecular weight ~89 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt P19447
Applications Western blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml (human recombinant protein)
Limitations This XPB antibody is available for research use only.
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Description

XPB (xeroderma pigmentosum type B) is an ATP-dependent DNA helicase in humans that is a part of the TFIIH transcription factor complex. This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.

Application Notes

Optimal dilution of the XPB antibody should be determined by the researcher.

Immunogen

Amino acids Q665-K715 from the human protein were used as the immunogen for the XPB antibody.

Storage

After reconstitution, the XPB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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