- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Viperin Antibody (N1126)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
N1126-100UG | 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 429 | |
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N1126-25UG | 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 25 ug | 219 |
|
| Species Reactivity | Human, Mouse, Rat, Dog |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Protein A affinity chromatography purified antibody |
| Buffer | 1X PBS, pH 7.4 |
| Gene ID | 91543 |
| Applications | Western blot : 3-6ug/ml |
| Limitations | This Viperin antibody is available for research use only. |
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Viral infection induces the interferon (IFN) response which triggers the production of an array of anti-viral proteins. Viperin (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible) is expressed in response to IFN-b binding to the IFN receptor, inducing the formation of the IFN-stimulated gene factor 3 complex which then binds to the Viperin promoter. It inhibits many DNA and RNA viruses through a diverse range of mechanisms and is involved in the PRR-mediated innate immune response. Viperin has been shown to be produced in response to TLR3 and TLR4 activation, but not TLR2 and TLR5. It may be involved in the TLR7 and TLR9-induced production of type I IFN by plasmacytoid dendritic cells (pDCs).
Provided assay concentrations are suggestions only, Viperin antibody titration may be required for optimal results.
A recombinant protein fragment from the N-terminal region of human Viperin was used as the immunogen for this antibody.
Aliquot the Viperin antibody and store frozen at -20oC or colder to avoid repeated freeze-thaw cycle.
Virus inhibitory protein endoplasmic reticulum associated interferon inducible, Virus inhibitory protein
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