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- Email: info@nsjbio.com
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Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene and belongs to the src gene family. It is mapped to 13q12. The deduced 1,338-amino acid protein has a calculated molecular mass of 150.6 kD. It has a 758-amino acid extracellular domain, followed by a 22-amino acid transmembrane region and a 558-amino acid cytoplasmic region containing a cluster of basic amino acids and a tyrosine kinase domain. sFLT-1 was identified in placenta, adult lung, kidney, liver and uterus. Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation.
The stated application concentrations are suggested starting amounts. Titration of the VEGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
An amino acid sequence from the C-terminus of human VEGF Receptor 1 (HVSEGKRRFTYDHAELERK) was used as the immunogen for this VEGFR antibody.
After reconstitution, the VEGFR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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