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Home >> Antibodies >> VEGF Receptor 2 Antibody

VEGF Receptor 2 Antibody [clone KDR657] (V2165)

  Catalog No Formulation Size Price (USD)  
V2165-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 329

V2165-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 129

V2165SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 359
Species Reactivity Human. Other species not known.
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name KDR657
Purity Protein G affinity chromatography
Buffer 1X PBS, pH 7.4
Gene ID 3791
Localization Cytoplasmic and cell surface
Applications Flow cytometry : 0.5-1ug/million cells in 0.1ml
Immunofluorescence:1-2ug/ml :
Limitations This VEGF receptor 2 antibody is available for research use only.

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Description

VEGF receptor 2, also known as CD309, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF receptor 2 is predominantly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF receptor 2 include VEGFA, VEGFC, VEGFD, and VEGF splice isoforms. Ligation of VEGF receptor 2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.

Application Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

Immunogen

Recombinant human VEGF receptor 2 protein was used as the immunogen for this antibody.

Storage

Store the VEGF Receptor 2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Alternate Names

CD309; Fetal liver kinase 1 (FLK-1); KDR; Kinase insert domain rec (a type III rec tyrosine kinase); KRD1; Ly73; Protein tyrosine kinase rec FLK1; Vascular endothelial growth factor recptor 2, VEGFR2 antibody, VEGF R2 antibody

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