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Home >> Antibodies >> UNC5C Antibody

UNC5C Antibody (R31843)

  Catalog No Formulation Size Price (USD)  
Image R31843 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) rat brain, 2) mouse brain and 3) human HeLa lysate with UNC5C antibody. Predicted molecular weight ~103 kDa, observed here at ~115 kDa.
Flow cytometry testing of human SH-SY5Y cells with UNC5C antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= UNC5C antibody.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt O95185
Applications Western blot : 0.1-0.5ug/ml
Flow cytometry : 1-3ug/million cells
Limitations This UNC5C antibody is available for research use only.
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Description

Netrin receptor UNC5C is a protein that in humans is encoded by the UNC5C gene. This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediates the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region.

Application Notes

Optimal dilution of the UNC5C antibody should be determined by the researcher.

Immunogen

Amino acids DLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGQ of human UNC5C were used as the immunogen for the UNC5C antibody.

Storage

After reconstitution, the UNC5C antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Cross
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