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Home >> Antibodies >> UchL1 Antibody

UchL1 Antibody [clone UCHL1/841] (V2921)

  Catalog No Formulation Size Price (USD)  
Image V2921-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V2921-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V2921SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Western blot testing of human brain lysate with UchL1 antibody (clone UCHL1/841). Predicted molecular weight ~25 kDa.
Western blot testing of human brain lysate with UchL1 antibody (clone UCHL1/841). Predicted molecular weight ~25 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a, kappa
Clone Name UCHL1/841
Purity Protein G affinity chromatography
UniProt P09936
Localization Cytoplasmic, ER membrane
Applications Western blot : 1-2ug/ml
Limitations This UchL1 antibody is available for research use only.
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Description

This mAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.

Application Notes

Optimal dilution of the UchL1 antibody should be determined by the researcher.

Immunogen

Recombinant human protein was used as the immunogen for the UchL1 antibody.

Storage

Store the UchL1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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