- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Tyrosyl-DNA phosphodiesterase 2 Antibody / TDP2 / ETS1 associated protein II (F54585)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54585-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F54585-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity purified |
| UniProt | O95551 |
| Localization | Nuclear, cytoplasmic |
| Applications | Flow cytometry : 1:25 (1x10e6 cells) Immunofluorescence : 1:25 Immunohistochemistry (FFPE) : 1:25 Western blot : 1:500-1:2000 |
| Limitations | This Tyrosyl-DNA phosphodiesterase 2 antibody is available for research use only. |
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This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
The stated application concentrations are suggested starting points. Titration of the Tyrosyl-DNA phosphodiesterase 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 246-272 from the human protein was used as the immunogen for the Tyrosyl-DNA phosphodiesterase 2 antibody.
Aliquot the Tyrosyl-DNA phosphodiesterase 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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