- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
TXNIP Antibody (N1119)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
N1119-100UG | 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 429 | |
|
|
N1119-25UG | 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 25 ug | 219 |
|
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Protein A affinity chromatography |
| Buffer | 1X PBS, pH 7.4 |
| Gene ID | 10628 |
| Applications | Western blot : 1-3ug/ml |
| Limitations | This TXNIP antibody is available for research use only. |
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TXNIP (Thioredoxin-interacting protein), also called VDUP1 (Vitamin D3 upregulated protein 1) is a member of the Arrestin family of signal transduction proteins. It is a potent tumor suppressor, blocking tumor growth via blocking cell cycle progression, and reduced expression of TXNIP is found in many tumors. One way TXNIP exerts its tumor suppressive function is by suppressing NF-kB activation, possibly via regulation of the NF-kB subunit p65.
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
A recombinant protein fragment from the N-terminal region of human TXNIP was used as the immunogen for this antibody.
Aliquot the TXNIP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Thioredoxin-interacting protein antibody, THIF
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