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Home >> Antibodies >> TSH Receptor Antibody

TSH Receptor Antibody (R32688)

  Catalog No Formulation Size Price (USD)  
Image R32688 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) rat brain and 2) mouse brain lysate with TSH Receptor antibody. Predicted molecular weight ~87 kDa (full length), ~44 kDa (beta subunit).
Availability 1-3 business days
Species Reactivity Mouse, Rat
Predicted Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
UniProt P16473
Applications Western Blot : 0.5-1ug/ml
Limitations This TSH Receptor antibody is available for research use only.
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Description

TSHR (Thyroid-Stimulating Hormone Receptor), also called LGR3, is mapped to 14q31.1. The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.

Application Notes

Optimal dilution of the TSH Receptor antibody should be determined by the researcher.

Immunogen

Amino acids 515-538 (ITLERWYAITFAMRLDRKIRLRHA) from the beta subunit of the human protein were used as the immunogen for the TSH Receptor antibody.

Storage

After reconstitution, the TSH Receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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