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Home >> Antibodies >> TSC2 Antibody

TSC2 Antibody (F47746)

  Catalog No Formulation Size Price (USD)  
Image F47746-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F47746-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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TSC2 antibody western blot analysis in 293 lysate. Predicted molecular weight ~200 kDa.
IHC analysis of FFPE human brain section using TSC2 antibody; Ab was diluted at 1:25.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P49815
Applications IHC (Paraffin) : 1:25
Western blot : 1:1000
Limitations This TSC2 antibody is available for research use only.
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Description

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

Application Notes

Titration of the TSC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 1397-1426 from the human protein was used as the immunogen for this TSC2 antibody.

Storage

Aliquot the TSC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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