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- Tel: 858.663.9055
- Email: info@nsjbio.com
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TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM]
Titration of the TRPM7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 1821-1850 from the human protein was used as the immunogen for this TRPM7 antibody.
Aliquot the TRPM7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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