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Home >> Antibodies >> TRPC6 Antibody

TRPC6 Antibody (R32851)

  Catalog No Formulation Size Price (USD)  
Image R32851 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) rat ovary and 2) rat lung lysate with TRPC6 antibody at 0.5ug/ml. Predicted molecular weight ~106 kDa.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Predicted Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
UniProt Q9Y210
Applications Western Blot : 0.5-1ug/ml
Limitations This TRPC6 antibody is available for research use only.
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Description

Transient receptor potential cation channel, subfamily C, member 6, also known as TRPC6, is a human gene encoding a protein of the same name. The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

Application Notes

Optimal dilution of the TRPC6 antibody should be determined by the researcher.

Immunogen

A recombinant human protein corresponding to amino acids K771-E875 was used as the immunogen for the TRPC6 antibody.

Storage

After reconstitution, the TRPC6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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