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Home >> Antibodies >> TRP1 Antibody / Tyrosinase-Related Protein-1 Antibody / TYRP1

TRP1 Antibody / Tyrosinase-Related Protein-1 Antibody / TYRP1 [clone TA99] (V3174)

  Catalog No Formulation Size Price (USD)  
Image V3174-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V3174-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V3174SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Bulk quote request
SDS-PAGE analysis of purified, BSA-free TRP1 antibody (clone TA99) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a, kappa
Clone Name TA99
Purity Protein G affinity chromatography
UniProt P17643
Localization Cytoplasmic
Applications Flow cytometry : 1-2ug/10^6 cells
Immunofluorescence : 1-2ug/ml
Immunohistochemistry (Frozen) : 1-2ug/ml for 30 min at RT
Limitations This TRP1 antibody is available for research use only.
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Description

It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Application Notes

The optimal dilution of the TRP1 antibody for each application should be determined by the researcher.

Immunogen

SK-MEL-23 cells were used as the immunogen for this TRP1 antibody.

Storage

Store the TRP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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