- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
The optimal dilution of the TRP1 antibody for each application should be determined by the researcher.
SK-MEL-23 cells were used as the immunogen for this TRP1 antibody.
Store the TRP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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