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Home >> Antibodies >> TrkC Antibody

TrkC Antibody (F50686)

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  Catalog No Formulation Size Price (USD)  
Image F50686-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F50686-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IHC analysis of FFPE human brain section using TrkC antibody; Ab was diluted at 1:100.
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IHC analysis of FFPE human brain section using TrkC antibody; Ab was diluted at 1:100.
TrkC antibody western blot analysis in U87-MG lysate. Observed molecular weight 95~145 kDa depending on glycosylation level.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q16288
Applications IHC (Paraffin) : 1:100
Western blot : 1:1000
Limitations This TrkC antibody is available for research use only.
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Description

TRKC, a member of the insuline receptor subfamily of Tyr protein kinases, is a receptor for neurotrophin-3 (NT-3). Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.

Application Notes

Titration of the TrkC antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This TrkC antibody was produced from rabbits immunized with a his tag recombinant protein of human TrkC.

Storage

Aliquot the TrkC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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