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Receptor for neurotrophin-3 (NT-3). This is a tyrosine-protein kinase receptor. Known substrates for the trk receptors are SHC1, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. [UniProt]
The stated application concentrations are suggested starting amounts. Titration of the TrkC antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 31-61 from the human protein was used as the immunogen for this TrkC antibody.
Store at 4oC for up to one month. For long term, aliquot the TrkC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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