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Home >> Antibodies >> TREX2 Antibody

TREX2 Antibody (R32573)

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  Catalog No Formulation Size Price (USD)  
Image R32573 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human 1) HeLa and 2) MCF7 cell lysate with TREX2 antibody at 0.5ug/ml. Predicted molecular weight ~31/26 kDa (isoforms 1/2), observed here at ~37 kDa.
Western blot testing of human 1) HeLa and 2) MCF7 cell lysate with TREX2 antibody at 0.5ug/ml. Predicted molecular weight ~31/26 kDa (isoforms 1/2), observed here at ~37 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt Q9BQ50
Localization Nuclear
Applications Western blot : 0.5-1ug/ml
Limitations This TREX2 antibody is available for research use only.
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Description

Three prime repair exonuclease 2 is an enzyme that in humans is encoded by the TREX2 gene. By genomic sequence analysis, the TREX2 gene is mapped to chromosome Xq28. This gene encodes a protein with 3' exonuclease activity. Enzymes with this activity are involved in DNA replication, repair, and recombination. Similarity to an E. coli protein suggests that this enzyme may be a subunit of DNA polymerase III, which does not have intrinsic exonuclease activity.

Application Notes

Differences in protocols and secondary/substrate sensitivity may require the TREX2 antibody to be titrated for optimal performance.

Immunogen

Amino acids E69-A279 from the human protein were used as the immunogen for the TREX2 antibody.

Storage

After reconstitution, the TREX2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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