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  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Home >> Antibodies >> TRBP2 Antibody

TRBP2 Antibody (N1132)

  Catalog No Formulation Size Price (USD)  
N1132-100UG 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 275

N1132-25UG 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 25 ug 129
Western blot testing of human samples with TRBP2 antibody at 6ug/ml.
Species Reactivity Human, Mouse, Primate
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Protein A Affinity Chromatography
Buffer 1X PBS, pH 7.4
Gene ID 6895
Applications Western blot : 5-10ug/ml
Limitations This TRBP2 antibody is available for research use only.

Description

TRBP2 (TAR (HIV-1) RNA binding protein 2) , along with Dicer and Argonaute-2, is part of the RISC (RNA induced silencing complex). As part of the RISC, TRBP2 is important in viral defense. Dicer cleaves dsRNA into siRNA. Through TRBP2-Dicer interaction, the siRNA template is loaded onto Argonaute-2, which cleaves encountered viral mRNA strands complementary to the loaded siRNA base-pair sequence.

Application Notes

Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

Immunogen

A recombinant protein fragment within the C-terminal region of TRBP2 was used as the immunogen for this antibody.

Storage

Aliquot the antibody and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles.

Alternate Names

Tar (HIV1) RNA binding protein, TRBP1

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