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Home >> Antibodies >> TLE1 Antibody / Transducin-like enhancer protein 1

TLE1 Antibody / Transducin-like enhancer protein 1 [clone 381CT18.5.1] (F40324)

  Catalog No Formulation Size Price (USD)  
Image F40324-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40324-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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TLE1 antibody western blot analysis in A549 lysate.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1
Clone Name 381CT18.5.1
Purity Purified
UniProt Q04724
Applications Western blot : 1:100-1:250
Limitations This TLE1 antibody is available for research use only.
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Description

Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Application Notes

Titration of the TLE1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 199-228 from the human protein was used as the immunogen for this TLE1 antibody.

Storage

Aliquot the TLE1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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