- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
TIM-1 Antibody (KIM-1) (R30715)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
R30715 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 429 |
| Availability | 1-3 business days |
| Species Reactivity | Rat |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal |
| UniProt | O54947 |
| Applications | Western blot : 0.5-1ug/ml Immunohistochemistry (FFPE) : 1-2ug/ml |
| Limitations | This TIM-1 antibody is available for research use only. |
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T-cell immunoglobulin and mucin domain-containing protein 1 (TIM-1) or Kidney injury molecule 1 (KIM-1), also known as HAVCR1 and HAVCR, is a protein that in humans is encoded by the KIM1 gene. Biochemical, mutational, and cell adhesion analyses confirm that TIM-1 is capable of homophilic interactions. The features identified in murine TIM1 is conserved in human protein. The protein is a receptor for virus through the infection of canine osteogenic sarcoma cells expressing HAVCR1 with HAV. Using a monoclonal antibody to mouse TIM-1, expression was seen after activation of naive T cells and on T cells differentiated in Th2-polarizing conditions. Ectopic expression during mouse T-cell differentiation leads to production of the Th2-type cytokine IL4, but not the Th1-type cytokine Ifng.
Titration of the TIM-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Amino acids 289-307 (HPRAEDNIYIIEDRSRGAE-rat) were used as the immunogen for this TIM-1 antibody.
The lyophilized TIM-1 antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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