- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Thyroid Peroxidase Antibody / TPO [clone AFFI-20] (RQ5170)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ5170 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | AFFI-20 |
| Purity | Affinity purified |
| UniProt | P07202 |
| Applications | Western blot : 1:500-1:2000 |
| Limitations | This Thyroid Peroxidase antibody is available for research use only. |
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The TPO gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA.
Optimal dilution of the Thyroid Peroxidase antibody should be determined by the researcher.
A synthetic peptide specific to human TPO / Thyroid peroxidase was used as the immunogen for the Thyroid Peroxidase antibody.
Store the Thyroid Peroxidase antibody at -20oC.
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