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Home >> Antibodies >> Thymidine kinase 1 Antibody / TK1

Thymidine kinase 1 Antibody / TK1 (R31883)

  Catalog No Formulation Size Price (USD)  
Image R31883 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human 1) HeLa and 2) SMMC cell lysate with Thymidine kinase 1 antibody. Expected/observed molecular weight ~25 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt P04183
Applications Western blot : 0.1-0.5ug/ml
Limitations This TK1 antibody is available for research use only.
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Description

Thymidine kinase 1, soluble (gene name TK1), is a human thymidine kinase. Thymidine kinase catalyzes the phosphorylation of thymidine to deoxythymidine monophosphate. This gene is mapped to 17q23.2-q25.3. It is estimated that the maximal size of the TK1 gene is 14 kb and its minimal size between 4 and 5 kb. The gene contains many noncoding inserts and numerous Alu sequences. There are two forms of this protein, which have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells.

Application Notes

Optimal dilution of the Thymidine kinase 1 antibody should be determined by the researcher.

Immunogen

Amino acids 2-234 of human TK1 were used as the immunogen for the Thymidine kinase 1 antibody.

Storage

After reconstitution, the Thymidine kinase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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