- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
TGFBR2 Antibody (F41742)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F41742-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F41742-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | P37173 |
| Applications | Western blot : 1:1000-2000 IHC (Paraffin) : 1:10-1:50 Immunofluorescence : 1:10-1:50 |
| Limitations | This TGFBR2 antibody is available for research use only. |
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This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
Titration of the TGFBR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 13-40 from the human protein was used as the immunogen for this TGFBR2 antibody.
Aliquot the TGFBR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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