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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Recognizes a protein of 71kDa, identified as Transcription Factor 4 (TCF4). It is a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome.
Optimal dilution of the TCF4 antibody should be determined by the researcher.
A portion of amino acids 365-671 from the human protein was used as the immunogen for this TCF4 antibody.
Store the TCF4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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