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Home >> Antibodies >> TANK-binding kinase 1 Antibody / TBK1 / NAK

TANK-binding kinase 1 Antibody / TBK1 / NAK (RQ7042)

  Catalog No Formulation Size Price (USD)  
Image RQ7042 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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IHC staining of FFPE mouse testis tissue with TANK-binding kinase 1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Western blot testing of 1) human 293T, 2) human HepG2, 3) human LNCaP, 4) rat brain, 5) rat C6, 6) mouse brain and 7) mouse Neuro-2a cell lysate with TANK-binding kinase 1 antibody. Predicted molecular weight: ~84 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q9UHD2
Applications Western blot : 0.5-1 ug/ml
Immunohistochemistry (FFPE) : 2-5ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This TANK-binding kinase 1 antibody is available for research use only.
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Description

Serine/threonine-protein kinase TBK1, also called TANK-binding kinase 1 or NF-kappa-B-activating kinase is an enzyme that in humans is encoded by the TBK1 gene. The gene was assigned to human chromosome 12q14.2. Serine/threonine kinase plays an essential role in regulating inflammatory responses to foreign agents. TBK1 and NF-kappa-B signaling are essential in KRAS mutant tumors, and established a general approach for the rational identification of codependent pathways in cancer.

Application Notes

Optimal dilution of the TANK-binding kinase 1 antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids M1-L729) was used as the immunogen for the TANK-binding kinase 1 antibody.

Storage

After reconstitution, the TANK-binding kinase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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