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Home >> Antibodies >> TACI Antibody / Transmembrane activator and CAML interactor

TACI Antibody / Transmembrane activator and CAML interactor (RQ4341)

  Catalog No Formulation Size Price (USD)  
Image RQ4341 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of recombinant human protein (1ng/lane) with TACI antibody at 0.5ug/ml. Predicted molecular weight ~32 kDa (full length, unmodified), observed here at ~40 kDa (AA 1-165 + purification tag).
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt O14836
Localization Membrane
Applications Western blot : 0.5-1ug/ml (recombinant human protein)
Limitations This TACI antibody is available for research use only.
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Description

Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B) is a protein that in humans is encoded by the TNFRSF13B gene. The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17.

Application Notes

Optimal dilution of the TACI antibody should be determined by the researcher.

Immunogen

A recombinant human protein corresponding to amino acids M1-S165 was used as the immunogen for the TACI antibody.

Storage

After reconstitution, the TACI antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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