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Home >> Antibodies >> Steroid sulfatase Antibody / Steryl-sulfatase / Arylsulfatase C

Steroid sulfatase Antibody / Steryl-sulfatase / Arylsulfatase C (RQ4367)

  Catalog No Formulation Size Price (USD)  
Image RQ4367 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human 1) HeLa, 2) placenta, 3) MCF7, 4) HepG2 and 5) PANC-1 lysate with Steroid sulfatase antibody at 0.5ug/ml. Predicted molecular weight ~65 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt P08842
Localization Nucleus
Applications Western blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This Steroid sulfatase antibody is available for research use only.
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Description

Steroid sulfatase (STS), or Steryl-sulfatase, formerly known as Arylsulfatase C, is a sulfatase enzyme involved in the metabolism of steroids. It is encoded by the STS gene. This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene.

Application Notes

Optimal dilution of the Steroid sulfatase antibody should be determined by the researcher.

Immunogen

A recombinant human protein corresponding to amino acids K297-E396 was used as the immunogen for the Steroid sulfatase antibody.

Storage

After reconstitution, the Steroid sulfatase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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