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Home >> Antibodies >> SRC-1 Antibody

SRC-1 Antibody (F42033)

  Catalog No Formulation Size Price (USD)  
Image F42033-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F42033-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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SRC-1 antibody western blot analysis in MDA-MB231 lysate.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q15788
Applications Western blot : 1:1000
Limitations This SRC-1 antibody is available for research use only.
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Description

Nuclear receptor coactivator 1/SRC-1 acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.

Application Notes

Titration of the SRC-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 594-625 from the human protein was used as the immunogen for this SRC-1 antibody.

Storage

Aliquot the SRC-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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