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Home >> Antibodies >> SOX7 Antibody

SOX7 Antibody (F52990)

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  Catalog No Formulation Size Price (USD)  
Image F52990-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F52990-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of lysate from 1) HCT116 cell line and 2) human heart tissue using SOX7 antibody at 1:1000. Predicted molecular weight: 42/49 kDa (isoforms 1/2).
Western blot analysis of lysate from 1) HCT116 cell line and 2) human heart tissue using SOX7 antibody at 1:1000. Predicted molecular weight: 42/49 kDa (isoforms 1/2).
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q9BT81
Applications Western blot : 1:1000
Limitations This SOX7 antibody is available for research use only.
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Description

Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'.

Application Notes

Titration of the SOX7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This SOX7 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 319-353 amino acids from the C-terminal region of human SOX7.

Storage

Aliquot the SOX7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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