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Home >> Antibodies >> SOD3 Antibody

SOD3 Antibody (F49928)

  Catalog No Formulation Size Price (USD)  
Image F49928-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F49928-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of SOD3 antibody and K562 lysate. Predicted molecular weight: 26~32 kDa.
IHC analysis of FFPE human lung carcinoma stained with SOD3 antibody
Flow cytometric analysis of K562 cells using SOD3 antibody (green) compared to a negative control (blue). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P08294
Localization Cytoplasm, extracellular matrix
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Flow Cytometry : 1:10-1:50
Limitations This SOD3 antibody is available for research use only.
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Description

SOD3 is a member of the superoxide dismutase(SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. This protein is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.

Application Notes

Titration of the SOD3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 7-36 from the human protein was used as the immunogen for this SOD3 antibody.

Storage

Aliquot the SOD3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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