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Home >> Antibodies >> SMURF1 Antibody

SMURF1 Antibody (R32324)

  Catalog No Formulation Size Price (USD)  
Image R32324 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) rat brain and 2) MCF7 lysate with SMURF1 antibody. Expected/observed molecular weight ~86 kDa.
Availability 1-3 business days
Species Reactivity Human, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt Q9HCE7
Applications Western blot : 0.1-0.5ug/ml
Limitations This SMURF1 antibody is available for research use only.
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Description

E3 ubiquitin-protein ligase SMURF1 is an enzyme that in humans is encoded by the SMURF1 gene. It is mapped to 7q22.1. This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.

Application Notes

Optimal dilution of the SMURF1 antibody should be determined by the researcher.

Immunogen

Amino acids DHNNRTTQFTDPRLHHIMNHQCQLKE of human SMURF1 were used as the immunogen for the SMURF1 antibody.

Storage

After reconstitution, the SMURF1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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