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Home >> Antibodies >> SMC2 Antibody

SMC2 Antibody (F40121)

  Catalog No Formulation Size Price (USD)  
Image F40121-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40121-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of SMC2 antibody and Jurkat lysate.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt O95347
Applications Western blot : 1:1000
Limitations This SMC2 antibody is available for research use only.
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Description

SMC2 is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Application Notes

Titration of the SMC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 1166-1197 from the human protein was used as the immunogen for this SMC2 antibody.

Storage

Aliquot the SMC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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