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- Tel: 858.663.9055
- Email: info@nsjbio.com
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SMC2 is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Titration of the SMC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 1166-1197 from the human protein was used as the immunogen for this SMC2 antibody.
Aliquot the SMC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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