• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Order
Home >> Antibodies >> SMAD2 Antibody

SMAD2 Antibody (F53216)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image F53216-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F53216-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
Bulk quote request
Western blot testing of SMAD2 antibody at 1:1000 dilution + NIH3T3 lysate; Predicted molecular weight: 52~60 kDa.
Western blot testing of SMAD2 antibody at 1:1000 dilution + NIH3T3 lysate; Predicted molecular weight: 52~60 kDa.
Availability 1-3 business days
Species Reactivity Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q15796
Applications Western blot : 1:1000
Limitations This SMAD2 antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Related Products

  • Applications : WB, IHC-P, FACS
    Reactivity : Human
  • Applications : WB, IHC-P, ICC
    Reactivity : Human
  • Applications : IF, WB, FACS, ELISA
    Reactivity : Human, Mouse
    Pred. Reactivity : Rat, Bovine, Pig, Chicken, Zebrafish, Drosophila
  • Applications : IF, WB, ELISA
    Reactivity : Human
    Pred. Reactivity : Mouse, Rat, Bovine, Zebrafish
  • Applications : WB, ELISA
    Reactivity : Human, Mouse, Rat
    Pred. Reactivity : Bovine, Pig, Chicken
  • Applications : IF, DB, ELISA
    Reactivity : Human
    Pred. Reactivity : Bovine, Chicken, Drosophila, Mouse, Pig, Rat, Zebrafish
  • Applications : WB, ELISA (peptide)
    Reactivity : Human, Mouse
    Pred. Reactivity : Cow

Description

SMAD2 is a receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. [UniProt]

Application Notes

Titration of the SMAD2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This SMAD2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 106-140 amino acids from the N-terminal region of human SMAD2.

Storage

Aliquot the SMAD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Related Products

   1.   View all SMAD2 antibodies

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.