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Home >> Antibodies >> Smad1 Antibody

Smad1 Antibody (F53187)

  Catalog No Formulation Size Price (USD)  
Image F53187-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F53187-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
Bulk quote request
Western blot testing of Smad1 antibody at 1:1000 dilution + mouse skeletal muscle lysate; Predicted molecular weight: 52~60 kDa.
Availability 1-3 business days
Species Reactivity Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P70340
Applications Western blot : 1:1000
Limitations This Smad1 antibody is available for research use only.
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Description

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) (By similarity). May play a role in the initiation and maintenance of spermatogenesis. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1 (By similarity). May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. [UniProt]

Application Notes

Titration of the Smad1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This Smad1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 154-187 amino acids from the central region of mouse Smad1.

Storage

Aliquot the Smad1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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