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Home >> Antibodies >> SLC2A1 Antibody / GLUT-1

SLC2A1 Antibody / GLUT-1 [clone GLUT1/7308] (V4685)

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  Catalog No Formulation Size Price (USD)  
Image V4685-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V4685-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V4685SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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IHC staining of FFPE human esophagus tissue with SLC2A1 antibody (clone GLUT1/7308). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human esophagus tissue with SLC2A1 antibody (clone GLUT1/7308). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human ovarian carcinoma tissue with SLC2A1 antibody (clone GLUT1/7308). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free SLC2A1 antibody (clone GLUT1/7308) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG
Clone Name GLUT1/7308
Purity Protein A/G affinity
UniProt P11166
Localization Cell Surface
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Limitations This SLC2A1 antibody is available for research use only.
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Description

Recognizes a protein of 55kDa, which is identified as GLUT-1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative).

Application Notes

Optimal dilution of the SLC2A1 antibody should be determined by the researcher.

Immunogen

A recombinant fragment of human GLUT1 protein (within amino acids 200-400) was used as the immunogen for the SLC2A1 antibody.

Storage

Aliquot the SLC2A1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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