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Home >> Antibodies >> SLC18A2 Antibody / VMAT2

SLC18A2 Antibody / VMAT2 [clone SLC18A2/7983] (V4123)

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  Catalog No Formulation Size Price (USD)  
Image V4123-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V4123-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V4123SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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IHC staining of FFPE human brain tissue with SLC18A2 antibody (clone SLC18A2/7983). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human brain tissue with SLC18A2 antibody (clone SLC18A2/7983). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human prostate tissue with SLC18A2 antibody (clone SLC18A2/7983). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free SLC18A2 antibody (clone SLC18A2/7983) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2, kappa
Clone Name SLC18A2/7983
Purity Protein A/G affinity
UniProt Q05940
Localization Cytoplasm
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT
Limitations This SLC18A2 antibody is available for research use only.
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Description

Neurotransmission depends on the regulated exocytotic release of chemical transmitter molecules. This requires the packaging of these substances into the specialized secretory vesicles of neurons and neuroendocrine cells, a process mediated by specific vesicular transporters. The family of genes encoding the vesicular transporters of monoamines (VMAT 1 and VMAT 2) and acetylcholine (VACht) have been cloned and functionally characterized. The sequence of these integral membrane proteins predicts twelve transmembrane domains and weak homology to a class of bacterial antibiotic resistance proteins. The vesicular transport of neurotransmitter molecules has been shown to be an active ATP- and proton dependent transport mechanism.

Application Notes

Optimal dilution of the SLC18A2 antibody should be determined by the researcher.

Immunogen

A recombinant fragment of human SLC18A2 protein was used as the immunogen for the SLC18A2 antibody.

Storage

Aliquot the SLC18A2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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