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Home >> Antibodies >> SIRT7 Antibody

SIRT7 Antibody (F49523)

  Catalog No Formulation Size Price (USD)  
Image F49523-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F49523-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of SIRT7 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SIRT7 gene (2).
IHC analysis of FFPE human hepatocarcinoma tissue stained with the SIRT7 antibody
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat, Bovine
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q9NRC8
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Limitations This SIRT7 antibody is available for research use only.
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  • Applications : WB, IHC-P
    Reactivity : Human, Mouse, Rat

Description

SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.

Application Notes

Titration of the SIRT7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 331-360 from the human protein was used as the immunogen for this SIRT7 antibody.

Storage

Aliquot the SIRT7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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