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Home >> Antibodies >> SIRT5 Antibody

SIRT5 Antibody (F43966)

  Catalog No Formulation Size Price (USD)  
Image F43966-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F43966-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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SIRT5 antibody western blot analysis in human placenta tissue lysate.
Western blot analysis of SIRT5 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (2) with the SIRT5 gene.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q9NXA8
Applications Western blot : 1:1000
Limitations This SIRT5 antibody is available for research use only.
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Description

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.

Application Notes

Titration of the SIRT5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 99-127 from the human protein was used as the immunogen for this SIRT5 antibody.

Storage

Aliquot the SIRT5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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