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Home >> Antibodies >> SIRT2 Antibody

SIRT2 Antibody [clone 1D4-H11-H11] (F54053)

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  Catalog No Formulation Size Price (USD)  
Image F54053-0.1ML Antibody in PBS with 50% glycerol and 0.03% ProClin 300 0.1 ml 399
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ICC/IF analysis of HeLa cells, fixed fixed by anhydrous methanol at -20oC, using SIRT2 antibody at 1:50 (green) and Histone H3.1 (pSer10) antibody at 1:200 (red).
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ICC/IF analysis of HeLa cells, fixed fixed by anhydrous methanol at -20oC, using SIRT2 antibody at 1:50 (green) and Histone H3.1 (pSer10) antibody at 1:200 (red).
Western blot testing of 1) rat PC12, 2) rat brain and 3) mouse brain lysates using SIRT2 antibody at 1:1000. Predicted molecular weight: multiple isoforms between 36-43 kDa.
Western blot testing of 1) rat cerebral cortex and 2) rat brain lysates using SIRT2 antibody at 1:1000. Predicted molecular weight: multiple isoforms between 36-43 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b
Clone Name 1D4-H11-H11
Purity Protein G affinity
UniProt Q8IXJ6
Applications Western blot : 1:1000
ICC/IF : 1:50
Limitations This SIRT2 antibody is available for research use only.
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Description

Sirtuin 2 is an NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors. Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. [UniProt]

Application Notes

The stated application concentrations are suggested starting points. Titration of the SIRT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A human recombinant protein was used as the immunogen for this SIRT2 antibody.

Storage

Store the SIRT2 antibody at -20oC.

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