- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
SIN1 Antibody / SAPK interacting protein 1 / MAPKAP1 (N1067)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
N1067-100UG | 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 429 | |
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N1067-25UG | 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 25 ug | 219 |
|
| Species Reactivity | Human, Mouse, Rat, Dog |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Protein A purified antibody |
| Buffer | 1X PBS, pH 7.4 |
| Gene ID | 79109 |
| Applications | Western blot : 1-3ug/ml |
| Limitations | This SIN1 antibody is available for research use only. |
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mTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.
Provided assay concentrations are suggestions only, SIN1 antibody titration may be required for optimal results.
A recombinant protein fragment from the C-terminal region of human SIN1 was used as the immunogen for this antibody.
Aliquot and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles.
MAPKAP1, SAPK interacting protein 1, MIP1
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