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Home >> Antibodies >> RUNX3 Antibody

RUNX3 Antibody [clone RNX864] (N1190)

  Catalog No Formulation Size Price (USD)  
Image N1190-100UG 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 429
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N1190-25UG 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 25 ug 219
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Western blot testing of human samples with RUNX3 antibody at 2 ug/ml. Predicted molecular weight: ~44 kDa, isoforms can be observed at 42-48 kDa.
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name RNX864
Purity Protein G Affinity Chromatography
Buffer 1X PBS, pH 7.4
Gene ID 864
Applications Western blot : 2-4ug/ml
Limitations This RUNX3 antibody is available for research use only.
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Description

The Runt family of transcription factors is involved in both normal cell development and carcinogenesis. Runt-related transcription factor 3 has been shown to be a tumor suppressor. Hypermethylation and mislocalization of the protein to the cytoplasm leads to low levels of RUNX3 and increased proliferation of breast and gastric tumor cells.

Application Notes

Provided assay concentrations are suggestions only, RUNX3 antibody titration may be required for optimal results.

Immunogen

A RUNX3 recombinant protein fragment was used as the immunogen for this antibody.

Storage

Aliquot the RUNX3 antibody and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles.

Alternate Names

Runt-related transcription factor 3

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