• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Order
Home >> Antibodies >> RTN4 Antibody / Reticulon 4 / Nogo A

RTN4 Antibody / Reticulon 4 / Nogo A (F53834)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image F53834-0.2ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.2 ml 399
Image
F53834-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 185
Bulk quote request
Western blot testing of human brain lysate with RTN4 antibody at 1:2000. Predicted molecular weight ~130 kDa but may be observed at up to ~220 kDa.
Western blot testing of human brain lysate with RTN4 antibody at 1:2000. Predicted molecular weight ~130 kDa but may be observed at up to ~220 kDa.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q9NQC3
Applications Western blot : 1:1000-2000
Limitations This RTN4 antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Related Products

Description

Reticulon-4 is a developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex (By similarity). Isoform 2 reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 inhibit BACE1 activity and amyloid precursor protein processing.

Application Notes

Titration of the RTN4 antibody may be required due to differences in protocols and substrate sensitivity.

Immunogen

A portion of amino acids 28-58 from the human protein was used as the immunogen for the RTN4 antibody.

Storage

Aliquot the RTN4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Related Products

   1.   View all RTN4 antibodies

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.