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Home >> Antibodies >> Retinoblastoma Antibody

Retinoblastoma Antibody (F51209)

  Catalog No Formulation Size Price (USD)  
Image F51209-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F51209-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of Retinoblastoma antibody and 293 lysate
IHC analysis of FFPE human testis tissue stained with Retinoblastoma antibody
FACS testing of human 293 cells with Retinoblastoma antibody (green) and a negative control pAb (blue). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Rat
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P06400
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Flow Cytometry : 1:10-1:50
Limitations This Retinoblastoma antibody is available for research use only.
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Description

RB1/Retinoblastoma is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.

Application Notes

Titration of the Retinoblastoma antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 858-886 from the human protein was used as the immunogen for this Retinoblastoma antibody.

Storage

Aliquot the Retinoblastoma antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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