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- Tel: 858.663.9055
- Email: info@nsjbio.com
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RB1/Retinoblastoma is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.
Titration of the Retinoblastoma antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 858-886 from the human protein was used as the immunogen for this Retinoblastoma antibody.
Aliquot the Retinoblastoma antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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