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Home >> Antibodies >> RET Antibody

RET Antibody (F50665)

  Catalog No Formulation Size Price (USD)  
Image F50665-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F50665-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of RET antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected with the RET gene (2).
IHC analysis of FFPE human breast carcinoma tissue stained with the RET antibody
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P07949
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Limitations This RET antibody is available for research use only.
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Description

RET, a member of the cadherin superfamily, is one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This protein plays a crucial role in neural crest development, and the gene can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations i are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma.

Application Notes

Titration of the RET antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 1012-1042 from the human protein was used as the immunogen for this RET antibody.

Storage

Aliquot the RET antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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