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Home >> Antibodies >> Recombinant TIMP2 Antibody

Recombinant TIMP2 Antibody [clone rTIMP2/2335] (V7896)

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  Catalog No Formulation Size Price (USD)  
Image V7896-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7896-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7896SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recmousemono
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IHC staining of FFPE human placenta with recombinant TIMP2 antibody (clone rTIMP2/2335). Required HIER: requires boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
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IHC staining of FFPE human placenta with recombinant TIMP2 antibody (clone rTIMP2/2335). Required HIER: requires boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant TIMP2 antibody (clone rTIMP2/2335) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Purified
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG1, kappa
Clone Name rTIMP2/2335
Purity Protein G affinity chromatography
UniProt P16035
Localization Cytoplasmic, cell surface, secreted
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant TIMP2 antibody is available for research use only.
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Description

It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Application Notes

Optimal dilution of the recombinant TIMP2 antibody should be determined by the researcher.

Immunogen

Amino acids DSGNDIYGNPI (N-terminal region) were used as the immunogen for the recombinant TIMP2 antibody.

Storage

Store the recombinant TIMP2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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