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Home >> Antibodies >> Recombinant Chromogranin A Antibody / Rabbit Monoclonal

Recombinant Chromogranin A Antibody / Rabbit Monoclonal [clone CHGA/1815R] (V3825)

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  Catalog No Formulation Size Price (USD)  
Image V3825-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V3825-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V3825SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recrabbitmono
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IHC analysis of FFPE human pancreas stained with recombinant Chromogranin A antibody (clone CHGA/1815R). Required HIER: steam sections in pH6 citrate buffer for 10-20 min.
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IHC analysis of FFPE human pancreas stained with recombinant Chromogranin A antibody (clone CHGA/1815R). Required HIER: steam sections in pH6 citrate buffer for 10-20 min.
SDS-PAGE analysis of purified, BSA-free recombinant Chromogranin A antibody (clone CHGA/1815R) as confirmation of integrity and purity.
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Chromogranin A antibody (clone CHGA/1815R). These results demonstrate the foremost specificity of the CHGA/1815R mAb.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name CHGA/1815R
Purity Protein A affinity chromatography
UniProt P10645
Localization Cytoplasmic
Applications Immunohistochemistry (FFPE) : 0.5-1ug/ml for 30 min at RT
Limitations This recombinant Chromogranin A antibody is available for research use only.
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Description

Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Application Notes

Optimal dilution of the recombinant Chromogranin A antibody should be determined by the researcher.

Immunogen

Recombinant human protein was used as the immunogen for the recombinant Chromogranin A antibody.

Storage

Store the recombinant Chromogranin A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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