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Home >> Antibodies >> Recombinant CD61 Antibody / Integrin beta 3 / ITGB3

Recombinant CD61 Antibody / Integrin beta 3 / ITGB3 [clone PMGP3-1R] (V3723)

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  Catalog No Formulation Size Price (USD)  
Image V3723-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V3723-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V3723SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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V3723IHC-7ML Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only* 7 ml 519
Microvalidated Recrabbitmono
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IHC testing of FFPE human renal cell carcinoma with CD61 antibody (clone PMGP3-1R). Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min followed by cooling at RT for 20 min.
IHC testing of FFPE human renal cell carcinoma with CD61 antibody (clone PMGP3-1R). Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min followed by cooling at RT for 20 min.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name PMGP3-1R
Purity Protein A affinity
UniProt P05106
Localization Cell surface, cytoplasmic
Applications IHC (FFPE) : 1-2ug/ml for 30 min at RT
Prediluted IHC only format : incubate for 30 min at RT (1)
Limitations This recombinant CD61 antibody is available for research use only.
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Description

CD61 associates with CD51 to form vitronectin receptor, or with CD41 to form the CD41/CD61 complex. The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 complex is implicated in tumor metastasis and adenoviral infection.

Application Notes

Titration of the recombinant CD61 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Immunogen

Human recombinant protein was used as the immunogen for the recombinant CD61 antibody.

Storage

Store the recombinant CD61 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Related Products

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   2.   View all recombinant antibodies

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